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Drug Interactions With the Rotavirus Vaccine

Rotavirus Vaccine Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when the rotavirus vaccine is combined with any of the drugs listed above.
Immune Globulins
Immune globulins decrease the effectiveness of live vaccines (like the rotavirus vaccine). Live vaccines should be postponed for six months after a dose of immune globulin, and any live vaccines received in the days immediately before a dose of immune globulin may need to be repeated.
If your child is taking an immunosuppressant, he or she may not receive the full benefit of the rotavirus vaccine, since the immune system may not be fully capable of responding to the vaccine. Probably more importantly, with some vaccines (especially live vaccines), people taking immunosuppressants may be at a higher risk of actually developing the infection (usually a mild form) from the vaccine.
Since the rotavirus vaccine is a live vaccine, it may not be recommended in some situations for children taking immunosuppressants.

Final Thoughts

It is possible that not all rotavirus vaccine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
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