Currently, there is no licensed vaccine for cholera in the United States; however, two recently developed vaccines are licensed and available in some other countries. Neither type of vaccine is recommended for travelers.
At the present time, the manufacture and sale of the only licensed cholera vaccine in the United States have been discontinued. The vaccine has not been recommended for travelers because of the brief and incomplete immunity if offers. Furthermore, no cholera vaccine requirements exist for entry to or exit from any country.
Two recently developed vaccines for cholera are licensed and available in some other countries. These vaccines include Dukoral™, manufactured by Biotech AB, and Mutacol®, manufactured by Berna. Both vaccines appear to provide somewhat better immunity, and fewer side effects, than the previously available vaccine for cholera; however, neither of these two vaccines is recommended for travelers, nor are they available in the United States.